Hi Deepak,
Have a look into the below link. It explains the activation/config of LIS & PIS.
http://help.sap.com/saphelp_scm40/helpdata/en/b4/0fc48e066041beb71f3a57dd04d1f2/content.htm
http://help.sap.com/saphelp_rc10/helpdata/en/70/8a09407448c442e10000000a1550b0/content.htm
Hope this helps.
Thanks,
Kalai.